Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.35 |
| ▸ | NPC1 | O15118 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404305 | 0.88 | PPARA (0.34) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9404504 | 0.87 | CPT1A (0.36) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9404383 | 0.81 | NPC1 (0.43) | RAB9ANPC1ATM | |
| Oxalic Acid SCHEMBL10584937 | 0.79 | NPC1 (0.44) | RAB9ANPC1ATM | |
| SCHEMBL7817015 | 0.72 | CHRM1 (0.31) | HRH1CHRM1 | |
| Oxalic Acid SCHEMBL9404438 | 0.69 | SLC6A3 (0.33) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9451917 | 0.67 | L3MBTL1 (0.34) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL7826658 | 0.67 | CHRM1 (0.35) | POLBCHRM1 | |
| SCHEMBL11360559 | 0.66 | CHRM1 (0.36) | MEN1KMT2AALDH1A1CHRM1 | |
| SCHEMBL9404421 | 0.64 | CHRM1 (0.33) | RAB9ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316718-B1 | AZACYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-15 | — | — | EP | claimed |
| US-5356912-A | 3-(5-isoxazolyl)-1-methyl-1,2,3,6-tetrahydropyridine useful for treating Alzheimer's disease | NOVO NORDISK A/S (DK) | 1994-10-18 | — | — | US | disclosed |
| US-5262427-A | Cognition activators for Alzheimer*s disease | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |
| EP-0316718-B1 | AZACYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-09-15 | — | — | EP | disclosed |
| EP-0316718-A2 | Azacyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-05-24 | — | — | EP | disclosed |