Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232296 | 0.78 | SELL (0.41) | — | |
| SCHEMBL30305680 | 0.65 | BCL2L1 (0.45) | DYRK1AHSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL3675894 | 0.65 | BCL2L1 (0.50) | DYRK1AHSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL9404792 | 0.64 | DRD2 (0.33) | CA1CA2CA6TDP1 | |
| SCHEMBL7855072 | 0.61 | FYN (0.56) | DYRK1ACA1CA2BACE1 | |
| SCHEMBL11725343 | 0.60 | ADCY6 (0.43) | DYRK1A | |
| SCHEMBL11881446 | 0.59 | HPGD (0.59) | HSP90AA1NQO1CA1BACE1TDP1 | |
| SCHEMBL12191968 | 0.58 | DRD1 (0.49) | CA1CA2CA4CA6 | |
| SCHEMBL3245289 | 0.57 | DRD2 (0.44) | HSP90AA1 | |
| SCHEMBL67497 | 0.55 | BACE1 (0.54) | NQO1CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313081-B1 | 2-Oxa-isocephem compounds, compositions containing the same and processes for preparing the same | OTSUKA PHARMA CO LTD (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-4950662-A | ANTIBIOTIC | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0313081-A2 | 2-Oxa-isocephem compounds, compositions containing the same and processes for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |