Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507984 | 0.88 | MEN1 (0.50) | MEN1KMT2AKDM4EMAPTACHE | |
| SCHEMBL460602 | 0.81 | MEN1 (0.50) | MEN1KMT2AACHE | |
| SCHEMBL10287315 | 0.81 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPTACHE | |
| SCHEMBL12507981 | 0.79 | ACHE (0.50) | MEN1KMT2AKDM4EMAPTACHE | |
| SCHEMBL12507663 | 0.77 | MEN1 (0.90) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL15024799 | 0.77 | MEN1 (0.53) | MEN1KMT2AACHE | |
| SCHEMBL27701976 | 0.75 | MEN1 (0.40) | MEN1KMT2AKDM4EMAPTACHE | |
| SCHEMBL22020517 | 0.74 | ACHE (0.48) | MEN1KMT2AKDM4EMAPTACHE | |
| SCHEMBL28469513 | 0.73 | BCHE (0.63) | KDM4EACHECYP1A2MAPK1ALDH1A1 | |
| SCHEMBL11717674 | 0.73 | KMT2A (0.83) | MEN1KMT2AKDM4EMAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283333-A | Cyclic compounds for forming complexes with urea, guanidine and amidine derivatives | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-01 | — | — | US | disclosed |
| US-5030728-A | Cyclic compounds for forming complexes with urea, guanidine and amidine derivatives | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1991-07-09 | — | — | US | disclosed |