Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706476 | 0.75 | MAPK1 (0.41) | MEN1KMT2AACHENSD2MAPK1 | |
| SCHEMBL9405015 | 0.75 | MEN1 (0.56) | MEN1KMT2AALDH1A1L3MBTL1ACHE | |
| SCHEMBL11679118 | 0.70 | PDE4A (0.38) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14370134 | 0.69 | ACHE (0.39) | MEN1KMT2ANPSR1ACHEBCHE | |
| SCHEMBL7479136 | 0.68 | GSR (0.34) | MEN1KMT2AALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL8081173 | 0.67 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL460602 | 0.66 | MEN1 (0.50) | MEN1KMT2AACHEBCHE | |
| SCHEMBL28238159 | 0.66 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL12507984 | 0.64 | MEN1 (0.50) | MEN1KMT2ANPSR1ACHEMAPK1 | |
| SCHEMBL22898892 | 0.64 | ACHE (0.37) | KMT2AACHEBCHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171254-A | Fused thieno[2,3-B]pyridine and thiazolo[5,4-B]pyridine compounds for inhibiting KSP kinesin activity | SCHERING CORP (US) | 2008-04-30 | — | — | CN | disclosed |