Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378848 | 0.69 | SLC6A4 (0.46) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| SCHEMBL9545809 | 0.69 | SLC6A4 (0.43) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| SCHEMBL7546727 | 0.69 | SLC6A4 (0.46) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| Hydrochloric Acid SCHEMBL7949501 | 0.69 | SLC6A4 (0.45) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| SCHEMBL16448777 | 0.66 | KDM1A (0.49) | KDM1A | |
| SCHEMBL728809 | 0.66 | SLC6A4 (0.43) | SLC6A4SLC6A3CYP2D6SLC6A2CYP2C9 | |
| SCHEMBL4784319 | 0.64 | KDM1A (0.46) | SLC6A4SLC6A3SLC6A2KDM1A | |
| SCHEMBL7948379 | 0.64 | SLC6A4 (0.43) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| Hydrochloric Acid SCHEMBL7755304 | 0.63 | KDM1A (0.45) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A | |
| SCHEMBL16404981 | 0.61 | TRPV3 (0.40) | SLC6A4SLC6A3CYP2D6SLC6A2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624152-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER. | PFIZER (US) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993012062-A1 | PROCESS FOR PREPARING KETONE ENANTIOMER | PFIZER INC. (US) | 1993-06-24 | — | — | WO | disclosed |