Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378848 | 0.94 | SLC6A4 (0.46) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL7546727 | 0.94 | SLC6A4 (0.46) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| Hydrochloric Acid SCHEMBL7949501 | 0.93 | SLC6A4 (0.45) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL7948379 | 0.87 | SLC6A4 (0.43) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| Mandelic Acid SCHEMBL5394925 | 0.81 | SLC6A4 (0.38) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL7949675 | 0.80 | AKR1B1 (0.43) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL7528171 | 0.72 | GRIN1 (0.50) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL4784319 | 0.72 | KDM1A (0.46) | SLC6A4SLC6A3SLC6A2KDM1A | |
| Hydrochloric Acid SCHEMBL7755304 | 0.71 | KDM1A (0.45) | SLC6A4OPRM1SLC6A3SLC6A2KCNH2 | |
| SCHEMBL9405484 | 0.69 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021917-A1 | DOPAMINE AND NORADRENERGIC REUPTAKE INHIBITORS IN TREATMENT OF SCHIZOPHRENIA | YALE UNIVERSITY (US) | 1993-11-11 | — | — | WO | disclosed |