Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405590 | 1.00 | HSD17B1 (0.50) | HSD17B1HSP90AB1HNF4AACMSDALOX5 | |
| SCHEMBL9407157 | 0.87 | HSP90AB1 (0.58) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL9407152 | 0.87 | HSP90AB1 (0.58) | HSP90AB1CA12CA1CA2CA7 | |
| SCHEMBL9405714 | 0.85 | CYP3A4 (0.52) | MEN1CYP3A4MAPTPPARGKMT2A | |
| SCHEMBL9405712 | 0.85 | CYP3A4 (0.52) | MEN1CYP3A4MAPTPPARGKMT2A | |
| SCHEMBL9405634 | 0.83 | HTT (0.46) | HSD17B1MGLLLMNAHTT | |
| SCHEMBL9405633 | 0.83 | HTT (0.46) | HSD17B1MGLLLMNAHTT | |
| SCHEMBL10339476 | 0.79 | RARB (0.52) | PPARG | |
| SCHEMBL9405584 | 0.78 | PDPK1 (0.56) | HSD17B1CA12CA1CA2CA7 | |
| SCHEMBL9325685 | 0.78 | PDPK1 (0.56) | HSD17B1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402110-B1 | Optical active compounds and liquid crystal compositions containing such compounds | WAKO PURE CHEM IND LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0315193-B1 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH & TELEPHONE (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5128062-A | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SUCH COMPOUNDS | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5059345-A | Spontaneous polarization in wide temperature range and high speed response | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0402110-A1 | Optical active compounds and liquid crystal compositions containing such compounds | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-12-12 | — | — | EP | disclosed |
| EP-0315193-A2 | Optically active compound and chiral liquid crystal composition containing the same | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1989-05-10 | — | — | EP | disclosed |