Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152047 | 0.82 | TACR1 (0.32) | DAOPIK3CGLMNATACR1MAPT | |
| SCHEMBL9287694 | 0.81 | LMNA (0.34) | SMN1; SMN2MEN1KMT2APIK3CGLMNA | |
| SCHEMBL9151716 | 0.78 | DAO (0.39) | SMN1; SMN2MEN1KMT2ADAOKDM4E | |
| SCHEMBL9151070 | 0.70 | — | — | |
| SCHEMBL9287269 | 0.68 | DAO (0.32) | DAO | |
| SCHEMBL9405604 | 0.68 | ACACB (0.45) | SMN1; SMN2MEN1KMT2ALMNAMAPT | |
| SCHEMBL6696769 | 0.67 | DAO (0.31) | DAO | |
| SCHEMBL9151978 | 0.66 | LMNA (0.35) | SMN1; SMN2DAOLMNATACR1MAPT | |
| SCHEMBL8370027 | 0.66 | LMNA (0.35) | SMN1; SMN2DAOLMNATACR1MAPT | |
| SCHEMBL11685381 | 0.65 | LMNA (0.33) | MEN1KMT2ADAOLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284966-A | Intermediates for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers | ZAMBON GROUP S.P.A. (IT) | 1994-02-08 | — | — | US | disclosed |