Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405848 | 0.98 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9406323 | 0.98 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9405865 | 0.98 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9406376 | 0.95 | RARB (0.47) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL20346161 | 0.93 | RARB (0.45) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9406155 | 0.90 | ALOX5 (0.40) | RARBHSD17B10RARARARGMAPT | |
| SCHEMBL9496950 | 0.89 | RARB (0.48) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9486012 | 0.89 | RARB (0.48) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL20346162 | 0.89 | RARB (0.44) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL10301942 | 0.88 | RARB (0.51) | RARBHSD17B10TSHRRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |