Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406166 | 0.95 | RARB (0.49) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9405865 | 0.93 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9405848 | 0.93 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9406323 | 0.93 | HSD17B10 (0.51) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL9406155 | 0.91 | ALOX5 (0.40) | RARBHSD17B10RARARARGMAPT | |
| SCHEMBL9495393 | 0.89 | RARB (0.44) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL20346161 | 0.88 | RARB (0.45) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL10301941 | 0.88 | RARB (0.46) | RARBHSD17B10TSHRRARARARG | |
| SCHEMBL6889224 | 0.88 | TAAR1 (0.39) | RARBRARARARGHRH3SMN1; SMN2 | |
| SCHEMBL9485788 | 0.87 | MPL (0.43) | RARBRARARARGCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |