Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408106 | 0.85 | CA12 (0.42) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL10339231 | 0.81 | LMNA (0.50) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL9531393 | 0.78 | LMNA (0.49) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL6131654 | 0.76 | KMT2A (0.50) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL9403525 | 0.74 | LMNA (0.47) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL9441423 | 0.74 | KMT2A (0.62) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| Bicarbonate SCHEMBL7458850 | 0.74 | LMNA (0.46) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL9441459 | 0.73 | KMT2A (0.51) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL10932608 | 0.73 | LMNA (0.43) | LMNATHRBCYP2C19KMT2ACYP3A4 | |
| SCHEMBL9621330 | 0.73 | KMT2A (0.45) | LMNATHRBCYP2C19KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6211806-A | — | — | None | — | — | JP | disclosed |
| JP-H06211806-A | RADIOSENSITIZER FOR HYPOXIC CELL | POLA CHEM IND INC | 1994-08-02 | — | — | JP | disclosed |