Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 3/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803810 | 0.81 | KMT2A (0.51) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL20350454 | 0.80 | CA12 (0.49) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL11360428 | 0.80 | CA12 (0.49) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL6131654 | 0.79 | KMT2A (0.50) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL9406399 | 0.78 | LMNA (0.44) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL8530813 | 0.78 | LMNA (0.59) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL29579255 | 0.78 | CA12 (0.53) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL11390072 | 0.77 | CA12 (0.64) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL920293 | 0.75 | LMNA (0.60) | LMNATHRBCYP2C19KMT2ACA12 | |
| SCHEMBL9272320 | 0.74 | KMT2A (0.54) | LMNATHRBCYP2C19KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325513-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-2-METHYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1993-04-07 | — | — | EP | claimed |
| EP-0324691-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-12-27 | — | — | EP | claimed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| JP-2000766-A | — | — | None | — | — | JP | disclosed |
| CN-1023318-C | Process for preparing 1-hydroxyalkyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-29 | — | — | CN | disclosed |
| CN-1023220-C | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitro imidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| US-5023361-A | Process for preparing hydroxyalkylating agents, the agents so obtained, and their use | RHONE-POULENC SANTE (FR) | 1991-06-11 | — | — | US | disclosed |
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925951-A | Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925952-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| JP-H02766-A | PREPARATION OF HYDROXYALKYLATION AGENT, HYDROXYLKYLATION AGENT OBTAINED AND METHOD FOR USING IT | RHONE POULENC SANTE | 1990-01-05 | — | — | JP | disclosed |