Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859942 | 1.00 | TRPV4 (0.33) | TRPV4CYP11B1CYP11B2 | |
| SCHEMBL9406851 | 0.96 | ALDH1A1 (0.33) | TRPV4 | |
| SCHEMBL9406856 | 0.96 | ALDH1A1 (0.33) | TRPV4 | |
| SCHEMBL9406965 | 0.95 | CYP1A2 (0.31) | TRPV4 | |
| SCHEMBL9406969 | 0.95 | CYP1A2 (0.31) | TRPV4 | |
| SCHEMBL9406982 | 0.95 | ALDH1A1 (0.35) | TRPV4 | |
| SCHEMBL9406958 | 0.95 | ALDH1A1 (0.35) | TRPV4 | |
| SCHEMBL9406953 | 0.95 | ALDH1A1 (0.35) | TRPV4 | |
| SCHEMBL9406937 | 0.95 | ALDH1A1 (0.35) | TRPV4 | |
| SCHEMBL9859076 | 0.95 | ALDH1A1 (0.35) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354502-A | Very large dielectric anisotropy and small birefringence | SEIKO EPSON CORPORATION (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0447565-A1 | 1,3-DIOXANE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | SEIKO EPSON CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0090183-B1 | POLYHALOGENATED AROMATIC COMPOUNDS | MERCK PATENT GmbH (DE) | 1986-02-19 | — | — | EP | disclosed |
| US-4551264-A | Polyhalogenoaromatic compounds for liquid crystal compositions | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0090183-A1 | Polyhalogenated aromatic compounds | MERCK PATENT GmbH (DE) | 1983-10-05 | — | — | EP | disclosed |