SCHEMBL9407146

SCHEMBL9407146

Fc1ccc(Cc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.48
PTGDR2 Q9Y5Y4 1/20 0.46
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.40
FOLH1 Q04609 1/20 0.40
SLC5A1 P13866 1/20 0.40
SLC5A2 P31639 1/20 0.40
TACR1 P25103 3/20 0.40
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9407148 0.92 PTGDR2 (0.46) DPP4PTGDR2FFAR1FFAR4ALDH1A1
SCHEMBL29484232 0.86 DPP4 (0.54) DPP4FFAR1FFAR4LMNAKMT2A
SCHEMBL29484236 0.86 DPP4 (0.54) DPP4FFAR1FFAR4LMNAKMT2A
SCHEMBL340250 0.86 DPP4 (0.58) DPP4ALDH1A1KMT2AFOLH1TACR1
SCHEMBL31070319 0.86 DPP4 (0.58) DPP4ALDH1A1KMT2AFOLH1TACR1
Hydrogen Sulfide SCHEMBL27779487 0.84 DPP4 (0.56) DPP4KMT2AFOLH1TACR1
SCHEMBL5188628 0.81 HTR2A (0.46) ALDH1A1SLC5A1SLC5A2
SCHEMBL11197019 0.81 HTR7 (0.49) DPP4FFAR1FFAR4ALDH1A1LMNA
SCHEMBL31488714 0.81 DPP4 (0.53) DPP4ALDH1A1KMT2AFOLH1
SCHEMBL27768912 0.81 KEAP1 (0.60) DPP4FFAR1FFAR4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290906-A Polymers from hydroquinone and 2,6-bisUp-fluorobenzoyle naphthalene for films and fibers with tensile strength TEIJIN LIMITED (JP) 1994-03-01 US disclosed