Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27530446 | 0.92 | MAPT (0.51) | LTA4HCES2CES1MAPTCA1 | |
| SCHEMBL124290 | 0.89 | PRNP (0.57) | LTA4HCES2CES1MAPTKMT2A | |
| SCHEMBL9654263 | 0.89 | CDC25B (0.56) | MAPTKMT2AHTTMEN1KDM4E | |
| SCHEMBL10385522 | 0.85 | MAPT (0.49) | LTA4HCES2CES1MAPTKMT2A | |
| SCHEMBL1754308 | 0.85 | AKR1C3 (0.58) | LTA4HCES2CES1MAPTCA1 | |
| Benzene SCHEMBL28318261 | 0.83 | AKR1C3 (0.61) | LTA4HCES2CES1MAPTKMT2A | |
| SCHEMBL28134072 | 0.82 | CYP1A2 (0.48) | LTA4HMAPTKMT2AHTTMEN1 | |
| SCHEMBL27873928 | 0.81 | AKR1C3 (0.65) | LTA4HCES2CES1MAPTHTT | |
| SCHEMBL9409888 | 0.81 | PTPN1 (0.54) | LTA4HKMT2AMEN1NPC1BAD | |
| SCHEMBL717723 | 0.80 | AKR1C3 (0.64) | MAPTNPSR1POLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290906-A | Polymers from hydroquinone and 2,6-bisUp-fluorobenzoyle naphthalene for films and fibers with tensile strength | TEIJIN LIMITED (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5191056-A | Molding materials | TEIJIN LIMITED (JP) | 1993-03-02 | — | — | US | disclosed |
| US-5037936-A | Bis(acid chloride) terminated polyaryl ether ketone oligomer | AMOCO CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0428743-A1 | POLY(ARYLENE ETHER KETONE), METHOD OF ITS PRODUCTION, AND ITS USE | TEIJIN LIMITED (JP) | 1991-05-29 | — | — | EP | disclosed |
| US-4959423-A | IMPROVED CRYSTALLIZATION RATES | AMOCO CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| US-4910289-A | Crystal structure; blend with poly(arylene sulfide) | AMOCO CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| US-4861915-A | Poly (aryl ether ketone) block copolymers | AMOCO CORPORATION (US) | 1989-08-29 | — | — | US | disclosed |
| US-4786694-A | Poly(aryl ether ketone) block copolymers | AMOCO CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |