Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654263 | 0.85 | CDC25B (0.56) | PTPN1NPC1TSHRMAPK1CNR2 | |
| SCHEMBL7498908 | 0.82 | PTGS2 (0.55) | PTPN1CNR1 | |
| SCHEMBL9407149 | 0.81 | LTA4H (0.48) | NPC1LTA4HBADMEN1KMT2A | |
| SCHEMBL11706745 | 0.78 | HSD17B14 (0.67) | PTPN1NPC1TSHRMAPK1LTA4H | |
| SCHEMBL5527342 | 0.77 | LTA4H (0.57) | NPC1TSHRMAPK1LTA4HBAD | |
| SCHEMBL30542686 | 0.77 | LTA4H (0.57) | NPC1TSHRMAPK1LTA4HBAD | |
| SCHEMBL209624 | 0.77 | ATM (0.67) | CTSLCTSKLTA4HATMTDP1 | |
| SCHEMBL2014295 | 0.76 | BCL2 (0.58) | PTPN1NPC1MAPK1CNR2BCL2 | |
| SCHEMBL11811012 | 0.75 | HSD17B14 (0.46) | PTPN1NPC1MAPK1CTSLCTSK | |
| SCHEMBL9407151 | 0.75 | LTA4H (0.55) | NPC1TSHRMAPK1LTA4HHSD17B14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581058-A1 | Polyaryl ether films | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5194561-A | PROCESS FOR THE PREPARATION OF AN AROMATIC POLYETHER IN THE PRESENCE OF FINELY DIVIDED CONDENSATION AUXILIARIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5081214-A | Mixture of Sodium Carbonate and Sodium Bicarbonate | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |
| EP-0412498-A2 | Process for preparation of an aromatic polyether | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-13 | — | — | EP | disclosed |
| EP-0412499-A2 | Process for the preparation of an aromatic polyether in the presence of finely dispersed condensation agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-13 | — | — | EP | disclosed |