SCHEMBL9654263

SCHEMBL9654263

O=C(c1ccc(F)cc1)c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.56
CNR2 P34972 4/20 0.53
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
BCL2 P10415 1/20 0.52
MCL1 Q07820 1/20 0.52
BAD Q92934 1/20 0.52
PLK1 P53350 1/20 0.51
GCGR P47871 3/20 0.49
MMP3 P08254 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
CNR1 P21554 1/20 0.47
NPC1 O15118 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
PTPN1 P18031 1/20 0.47
MEN1 O00255 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9407149 0.89 LTA4H (0.48) BADNPC1MEN1HTTKMT2A
SCHEMBL547632 0.85 CDC25B (0.69) CDC25BCNR2NR4A1NR4A2NR4A3
SCHEMBL27530446 0.85 MAPT (0.51) NPC1TSHRMAPK1MEN1HTT
SCHEMBL29522736 0.85 CDC25B (0.69) CDC25BCNR2NR4A1NR4A2NR4A3
SCHEMBL9409888 0.85 PTPN1 (0.54) CDC25BCNR2BCL2MCL1BAD
SCHEMBL7189887 0.84 CDC25B (0.68) CDC25BCNR2NR4A1NR4A2NR4A3
SCHEMBL5382022 0.84 LIG1 (0.61) CDC25BCNR2NR4A1NR4A2NR4A3
Naphthalene SCHEMBL11467392 0.83 CDC25B (0.67) CDC25BCNR2NR4A1NR4A2NR4A3
SCHEMBL8418472 0.83 CYP1B1 (0.50) NPC1TSHRMAPK1MEN1HTT
SCHEMBL1754308 0.82 AKR1C3 (0.58) CDC25BNR4A1NPC1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101463128-B Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same JILIN UNIVERSITY (CN) 2011-12-07 CN claimed
CN-101463128-A Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same UNIV JILIN (CN) 2009-06-24 CN claimed
CN-101219968-A Cyanogens radical containing phenyl-hydrochinone monomer, preparation method and application thereof UNIV JILIN (CN) 2008-07-16 CN claimed
CN-1257144-C 1,4-di-(4-fluorophenyl carbonyl) naphthalene, and its synthesizing method and use in synthesizing polymer material UNIV JILIN (CN) 2006-05-24 CN claimed
CN-1580027-A 1,4-di-(4-fluorophenyl carbonyl) naphthalene, and its synthesizing method and use in synthesizing polymer material UNIV JILIN (CN) 2005-02-16 CN claimed
CN-117321115-A Polyether resin, process for producing the same, and use thereof 大阪燃气化学有限公司 2023-12-29 CN disclosed
CN-102702507-B Strong basicity polyarylether ionomer and Synthesis and applications thereof SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-03-02 CN disclosed
CN-103289085-A 2,6-naphthalic acid based heterocyclic polyaryletherketone and preparation method thereof UNIV HUAQIAO 2013-09-11 CN disclosed
CN-102702507-A Strongly alkaline polyarylether ionomer and preparation and application thereof UNIV SOUTH CHINA TECH 2012-10-03 CN disclosed
CN-101463128-B Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same JILIN UNIVERSITY (CN) 2011-12-07 CN disclosed
CN-101463186-B Composite type proton conduction membrane material containing amino-sulfonic group and preparation thereof UNIV JILIN 2011-01-26 CN disclosed
CN-101463128-A Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same UNIV JILIN (CN) 2009-06-24 CN disclosed
CN-101463186-A Composite type proton conduction membrane material containing amino-sulfonic group and preparation thereof UNIV JILIN (CN) 2009-06-24 CN disclosed
CN-101219968-A Cyanogens radical containing phenyl-hydrochinone monomer, preparation method and application thereof UNIV JILIN (CN) 2008-07-16 CN disclosed
CN-1257144-C 1,4-di-(4-fluorophenyl carbonyl) naphthalene, and its synthesizing method and use in synthesizing polymer material UNIV JILIN (CN) 2006-05-24 CN disclosed
CN-1580027-A 1,4-di-(4-fluorophenyl carbonyl) naphthalene, and its synthesizing method and use in synthesizing polymer material UNIV JILIN (CN) 2005-02-16 CN disclosed
EP-0518196-A1 Polyethers based on 9,9-BIS-perfluoroalkyl-3,6-dihydroxy-xanthene or 9-aryl-9-perfluoroalkyl-3,6-dihydroxy-xanthene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-16 EP disclosed