Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407921 | 1.00 | MEN1 (0.53) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL2909279 | 0.95 | KMT2A (0.56) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL2909284 | 0.95 | KMT2A (0.56) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL2909281 | 0.95 | KMT2A (0.56) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL9698864 | 0.89 | CA1 (0.61) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL9698869 | 0.89 | CA1 (0.61) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL9408027 | 0.84 | CA1 (0.56) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL9408024 | 0.84 | CA1 (0.56) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL4900542 | 0.82 | KMT2A (0.66) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL4900549 | 0.82 | KMT2A (0.66) | MEN1KMT2ACA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609032-A1 | Aromatic imine compounds, pharmaceutical composition thereof, useful as protein synthesis inhibitors | NORSK HYDRO A/S (NO) | 1994-08-03 | — | — | EP | claimed |
| EP-0609032-A1 | Aromatic imine compounds, pharmaceutical composition thereof, useful as protein synthesis inhibitors | NORSK HYDRO A/S (NO) | 1994-08-03 | — | — | EP | disclosed |