Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432758 | 0.88 | CYP3A4 (0.39) | CYP3A4ALDH1A1TDP1HPGDTP53 | |
| SCHEMBL27687849 | 0.78 | TDP1 (0.43) | CYP3A4ALDH1A1TDP1HPGDTP53 | |
| SCHEMBL1046649 | 0.76 | CYP3A4 (0.56) | CYP3A4ALDH1A1TDP1HPGDTRPA1 | |
| SCHEMBL694286 | 0.74 | CYP3A4 (0.40) | CYP3A4ALDH1A1TDP1HPGDTRPA1 | |
| SCHEMBL11429926 | 0.74 | CYP3A4 (0.46) | CYP3A4ALDH1A1TDP1HPGDTRPA1 | |
| SCHEMBL9408113 | 0.74 | CYP3A4 (0.43) | CYP3A4ALDH1A1TDP1HPGDTP53 | |
| SCHEMBL12945123 | 0.73 | CYP3A4 (0.63) | CYP3A4ALDH1A1TDP1HPGDTRPA1 | |
| SCHEMBL140959 | 0.73 | CYP3A4 (0.34) | CYP3A4ALDH1A1TDP1TP53HSD17B10 | |
| SCHEMBL7570309 | 0.73 | CYP3A4 (0.39) | CYP3A4ALDH1A1TDP1HPGDTRPA1 | |
| SCHEMBL8907729 | 0.71 | ALDH1A1 (0.45) | CYP3A4ALDH1A1TDP1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352527-A | Having heat resistant protective layer containing amine-modified polysiloxane, polyisocyanate and reaction product between these | RICOH COMPANY, LTD. (JP) | 1994-10-04 | — | — | US | claimed |