Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269913 | 0.86 | NPC1 (0.42) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL9265708 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL9268510 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL4357048 | 0.83 | NPC1 (0.50) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL9267379 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL13700419 | 0.81 | GABRA1 (0.37) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL9258342 | 0.80 | FABP4 (0.42) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL28349955 | 0.72 | NPC1 (0.37) | GABRA1GABRB2NPC1RAB9AGABRB1 | |
| SCHEMBL11616334 | 0.71 | NPC1 (0.39) | NPC1RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL13273869 | 0.71 | NPC1 (0.39) | GABRA1NPC1RAB9AGABRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |