Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408370 | 0.96 | MAPT (0.37) | MAPTNPC1STAT1RAB9ASMN1; SMN2 | |
| SCHEMBL9408354 | 0.90 | THRB (0.39) | FFAR4CYP2C9SLC6A3 | |
| SCHEMBL9408344 | 0.90 | THRB (0.39) | FFAR4CYP2C9SLC6A3 | |
| SCHEMBL9408262 | 0.86 | THRB (0.41) | FFAR4CYP2C9SLC6A3 | |
| SCHEMBL9408251 | 0.86 | THRB (0.41) | FFAR4CYP2C9SLC6A3 | |
| SCHEMBL9408293 | 0.86 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2FFAR1SLC6A3 | |
| SCHEMBL9408302 | 0.86 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2FFAR1SLC6A3 | |
| SCHEMBL9408244 | 0.83 | BCL2L1 (0.39) | MAPTCYP2C9BCL2L1MCL1LMNA | |
| SCHEMBL9408288 | 0.83 | DPP4 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1SLC6A3 | |
| SCHEMBL9408253 | 0.83 | HDAC2 (0.35) | MAPTNPC1RAB9AALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595144-A1 | Cyclohexyl alkenoates as components of liquid crystalline mixtures | F. HOFFMANN-LA ROCHE AG (CH) | 1994-05-04 | — | — | EP | disclosed |