⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11617040 | 0.97 | — | — | |
| Hydroxyamine SCHEMBL28202053 | 0.93 | TRPM8 (0.39) | — | |
| SCHEMBL27606192 | 0.85 | TRPM8 (0.34) | — | |
| SCHEMBL7340730 | 0.80 | IDO1 (0.38) | — | |
| SCHEMBL5728 | 0.71 | — | — | |
| SCHEMBL2124100 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL7395872 | 0.69 | — | — | |
| SCHEMBL28922581 | 0.69 | — | — | |
| SCHEMBL1012703 | 0.69 | — | — | |
| SCHEMBL56595 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4478 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120137498-A | Heat-resistant paint for inner wall of pipeline and preparation method thereof | 安徽合众管业科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| WO-2025120654-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TIVOZANIB HYDROCHLORIDE HYDRATE | NATCO PHARMA LIMITED (IN) | 2025-06-12 | — | — | WO | claimed |
| US-11165098-B2 | Substituted isoxazoles for lithium batteries | GOTION, INC. (US) | 2021-11-02 | — | — | US | claimed |
| WO-2021159993-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE (IRAK) /FMS-LIKE RECEPTOR TYROSINE KINASE (FLT3), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | PHARMABLOCK SCIENCES (NANJING) , INC. (CN) | 2021-08-19 | — | — | WO | claimed |
| CN-112876422-A | Chlorogenic acid derivative used as preservative and preparation method thereof | 谢天龙 | 2021-06-01 | — | — | CN | claimed |
| CN-107636871-B | Substituted isoxazoles for lithium batteries | 国轩高科美国研究院 | 2021-02-09 | — | — | CN | claimed |
| CN-111978267-A | Tritium-labeled sulfamethoxazole with high specific activity and preparation method thereof | 华中农业大学 | 2020-11-24 | — | — | CN | claimed |
| CN-107721941-B | Preparation method of 3-amino-5-methyl isoxazole | 浦拉司科技（上海）有限责任公司 | 2020-05-22 | — | — | CN | claimed |
| CN-107022896-B | Polyurethane -3- amino -5- methylisoxazole fiber producing processes and its application in food in the enrichment detection of heavy metal | 浙江工商大学 | 2019-04-16 | — | — | CN | claimed |
| CN-109251180-A | A kind of chemical synthesis process of 3- isoxazolyl acetic acid benzyl rouge | 盐城锦明药业有限公司 | 2019-01-22 | — | — | CN | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0673784-A2 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| CN-1019397-B | The method for preparing diphosphonic acid derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1992-12-09 | — | — | CN | claimed |
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | claimed |
| CN-88102021-A | Diphosphonic acid derivative and contain the medicine of this derivative | — | 1988-10-05 | — | — | CN | claimed |
| US-4477661-A | Process for the preparation of 4-hydroxy-3-(heterocyclocarbamoyl)-2H-1,2-benzothiazine-1,1-dioxides | WARNER-LAMBERT COMPANY (US) | 1984-10-16 | — | — | US | claimed |
| US-4225721-A | INTERMEDIATES FOR 3-AMINO-5-METHYL ISOOXAZOLE | SOGO PHARMACEUTICAL COMPANY, LTD. (JP) | 1980-09-30 | — | — | US | claimed |
| US-4024136-A | Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide | WARNER-LAMBERT COMPANY (US) | 1977-05-17 | — | — | US | claimed |
| US-3960856-A | Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide | WARNER-LAMBERT COMPANY (US) | 1976-06-01 | — | — | US | claimed |
| US-3957772-A | PROCESS FOR THE PREPARATION OF 4-HYDROXY-3-(5-METHYL-3-ISOXAZOLYLCARBAMOYL)-2-METHYL-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE | WARNER-LAMBERT COMPANY (US) | 1976-05-18 | — | — | US | claimed |