SCHEMBL9408335

SCHEMBL9408335

C=CCC(C(=O)O)C1CCC([C@H]2CC[C@H](c3ccc(Cl)cc3)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.40
BCL2L1 Q07817 2/20 0.39
MCL1 Q07820 2/20 0.39
PRCP P42785 5/20 0.38
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
HIF1A Q16665 1/20 0.36
CCR1 P32246 5/20 0.35
USP5 P45974 1/20 0.34
DEGS1 O15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408355 0.96 IDO1 (0.42) IDO1BCL2L1MCL1PRCPMAPT
SCHEMBL9408221 0.89 USP5 (0.35) PRCPMAPTLMNACYP1A2CYP2C9
SCHEMBL9408289 0.88 SLC6A2 (0.36) MAPTMEN1TP53TSHRKMT2A
SCHEMBL9408392 0.88 CCR2 (0.37) PRCPMEN1KMT2ACCR1USP5
SCHEMBL9408278 0.88 SLC6A2 (0.36) MAPTMEN1TP53TSHRKMT2A
SCHEMBL9408187 0.85 FFAR4 (0.35) BCL2L1MCL1MAPTLMNACYP2C9
SCHEMBL9408328 0.84 USP5 (0.39) USP5
SCHEMBL9408223 0.84 ALDH1A1 (0.39) MAPTLMNATP53TSHRUSP5
SCHEMBL9408270 0.84 CCR2 (0.39)
SCHEMBL9408337 0.84 GRIA1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0595144-A1 Cyclohexyl alkenoates as components of liquid crystalline mixtures F. HOFFMANN-LA ROCHE AG (CH) 1994-05-04 EP disclosed