Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839557 | 0.87 | SLC6A4 (0.53) | ALOX15ALOX12 | |
| SCHEMBL10839564 | 0.87 | SLC6A4 (0.53) | ALOX15ALOX12 | |
| SCHEMBL8244070 | 0.83 | ALOX15 (0.50) | ALOX15ALOX12LDHAHTTCYP17A1 | |
| SCHEMBL20061670 | 0.80 | ALOX15 (0.60) | ALOX15ALOX12LDHAHTTCYP17A1 | |
| SCHEMBL13003651 | 0.79 | ALOX15 (0.46) | ALOX15ALOX12LDHAHTTCYP17A1 | |
| SCHEMBL11218889 | 0.79 | ALOX15 (0.46) | ALOX15ALOX12LDHAHTTCYP17A1 | |
| SCHEMBL4659448 | 0.78 | LDHA (0.42) | ALOX15ALOX12LDHALMNAHTT | |
| SCHEMBL8012680 | 0.77 | LDHA (0.59) | ALOX15LDHALMNAHTTKDM4E | |
| SCHEMBL31329364 | 0.77 | LDHA (0.59) | ALOX15LDHALMNAHTTKDM4E | |
| SCHEMBL15881661 | 0.77 | LDHA (0.55) | ALOX15ALOX12LDHALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623601-A1 | N-(3-Fluorobenzyl)heterocyclic derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-11-09 | — | — | EP | disclosed |