Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408821 | 0.84 | NPC1 (0.56) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL7703339 | 0.83 | NPC1 (0.71) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1275936 | 0.83 | NPC1 (0.71) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL29489567 | 0.83 | NPC1 (0.71) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL110113 | 0.83 | NPC1 (0.71) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL13716942 | 0.81 | NPC1 (0.64) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL10598824 | 0.81 | NPC1 (1.00) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL18375849 | 0.81 | NPC1 (0.68) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL105385 | 0.81 | NPC1 (0.68) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL27164725 | 0.81 | NPC1 (0.46) | NPC1RAB9APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |