SCHEMBL9408743

SCHEMBL9408743

CCCCOC(=O)C(Sc1nc(OC)cc(OC)n1)C(C)(C)Cl

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 15/20 0.42
PPARG P37231 12/20 0.41
PTGES O14684 10/20 0.40
PSEN1 P49768 2/20 0.39
PTGS2 P35354 1/20 0.39
ADORA3 P0DMS8 2/20 0.36
AR P10275 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9408720 0.88 ALOX5 (0.44) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL8943363 0.88 ALDH1A1 (0.40) ADORA3ADORA1
SCHEMBL9408782 0.86 ALOX5 (0.41) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408921 0.86 ALOX5 (0.43) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408598 0.85 ALOX5 (0.42) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408687 0.85 ALOX5 (0.40) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408767 0.85 ALOX5 (0.42) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408710 0.85 ALOX5 (0.42) ALOX5PPARGPTGESPSEN1PTGS2
SCHEMBL9408612 0.83 EDNRB (0.45) ALOX5PPARGPTGESPSEN1
SCHEMBL9408836 0.78 ALOX5 (0.38) ALOX5PPARGPTGESPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593998-A1 Pyrimidinylthioalkane herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-04-27 EP disclosed