Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538266 | 1.00 | APLNR (0.39) | APLNRSIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL943424 | 1.00 | APLNR (0.39) | APLNRSIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9408942 | 1.00 | APLNR (0.39) | APLNRSIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2932564 | 1.00 | APLNR (0.39) | APLNRSIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2932560 | 1.00 | APLNR (0.39) | APLNRSIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7785952 | 0.77 | SIGMAR1 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1810527 | 0.72 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22614581 | 0.72 | APLNR (0.42) | APLNR | |
| SCHEMBL22614578 | 0.72 | APLNR (0.42) | APLNR | |
| SCHEMBL1512248 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609518-A1 | Optically active aminopyridine derivative and use thereof | THE GREEN CROSS CORPORATION (JP) | 1994-08-10 | — | — | EP | disclosed |