Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 6/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409163 | 0.89 | MAPT (0.50) | MAPTHTTCXCL8RAB9ANPC1 | |
| SCHEMBL9409045 | 0.80 | KDM4E (0.53) | MAPTHTTNPC1PIM1ALDH1A1 | |
| SCHEMBL9409050 | 0.79 | CSF1R (0.49) | MAPTHTTRAB9ANPC1CSF1R | |
| SCHEMBL9409089 | 0.79 | FABP4 (0.61) | MAPTMEN1KMT2AKDM4ESIRT2 | |
| SCHEMBL4748692 | 0.78 | MAP2K1 (0.63) | MAPTHTTMAP2K2MAP2K1 | |
| SCHEMBL30172477 | 0.78 | MAP2K1 (0.63) | MAPTHTTMAP2K2MAP2K1 | |
| SCHEMBL29127196 | 0.78 | MAPT (0.54) | MAPTHTTCSF1RPIM1PIM2 | |
| SCHEMBL30664062 | 0.78 | MAPT (0.54) | MAPTHTTCSF1RPIM1PIM2 | |
| SCHEMBL16571363 | 0.77 | MAP2K1 (0.66) | MAPTHTTCXCL8RAB9ANPC1 | |
| SCHEMBL14426312 | 0.77 | MAP2K1 (0.75) | MAPTHTTMAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |