Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.61 |
| ▸ | FABP3 | P05413 | 1/20 | 0.57 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 4/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16992722 | 0.91 | FABP4 (0.67) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL9409047 | 0.89 | MAPT (0.55) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL30320327 | 0.84 | FABP4 (0.80) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL355549 | 0.84 | FABP4 (0.80) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL9691899 | 0.82 | FABP4 (0.77) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL6142375 | 0.82 | FABP4 (0.84) | FABP4FABP3FABP5CDC25BAKR1C3 | |
| SCHEMBL10424663 | 0.82 | SIRT2 (0.62) | FABP4SIRT2SIRT1MAPTHPGD | |
| SCHEMBL9409097 | 0.82 | MAPT (0.57) | FABP4AKR1C3AKR1C2SIRT2SIRT1 | |
| SCHEMBL9409083 | 0.81 | MAPT (0.61) | MEN1LMNAPTGS2KMT2ASIRT2 | |
| SCHEMBL9409100 | 0.80 | MAPT (0.59) | MEN1LMNAPTGS2KMT2ASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |