Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | CDC25C | P30307 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409164 | 0.95 | CDC25B (0.57) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL9409083 | 0.85 | MAPT (0.61) | TSHRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL9409100 | 0.84 | MAPT (0.59) | TSHRLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL21312102 | 0.82 | CDC25B (0.78) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL10834558 | 0.81 | CDC25B (0.77) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL10438008 | 0.80 | KDM4E (0.68) | TSHRLMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24494688 | 0.80 | CDC25B (0.63) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL3944845 | 0.80 | TSHR (0.69) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL6888975 | 0.80 | TSHR (0.81) | CDC25BCDC25ACDC25CTSHRLMNA | |
| SCHEMBL8834884 | 0.80 | CDC25B (0.59) | CDC25BCDC25ACDC25CTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |