Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25C | P30307 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409092 | 0.95 | CDC25B (0.63) | CDC25BCDC25ACDC25CKDM4EHSD17B10 | |
| SCHEMBL9409100 | 0.91 | MAPT (0.59) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL9409083 | 0.89 | MAPT (0.61) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL24494688 | 0.84 | CDC25B (0.63) | CDC25BCDC25ACDC25CKDM4EHSD17B10 | |
| SCHEMBL9409047 | 0.84 | MAPT (0.55) | CDC25BKDM4ELMNAHPGDMAPT | |
| SCHEMBL9409103 | 0.83 | ALDH1A1 (0.50) | KDM4EHSD17B10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9409337 | 0.82 | CSF1R (0.49) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9409108 | 0.80 | TSHR (0.51) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL9409039 | 0.80 | SIRT2 (0.56) | KDM4EALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL9409193 | 0.79 | CDC25B (0.60) | CDC25BCDC25ACDC25CKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |