Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 7/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409082 | 0.72 | EGFR (0.43) | APPCXCR2MAPTMEN1KMT2A | |
| SCHEMBL10733814 | 0.64 | MAPT (0.68) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9381294 | 0.63 | APP (0.70) | APPNR1H2NR1H3BRD4BPTF | |
| SCHEMBL30557775 | 0.63 | EGFR (0.62) | CXCR2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL84534 | 0.63 | EGFR (0.62) | CXCR2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13206625 | 0.62 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL22623757 | 0.62 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8026004 | 0.62 | HSD17B10 (0.42) | CXCR2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2173695 | 0.62 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28969955 | 0.60 | MAPT (0.65) | CXCR2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |