Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623757 | 1.00 | MEN1 (0.56) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL13206625 | 1.00 | MEN1 (0.56) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL19255620 | 0.92 | MEN1 (0.49) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL19003848 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8463734 | 0.80 | RAB9A (0.49) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL8611610 | 0.80 | RAB9A (0.49) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL9912528 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2AATMRAB9AALDH1A1 | |
| SCHEMBL22792110 | 0.78 | GPR3 (0.60) | MEN1KMT2AATMALDH1A1HSD17B10 | |
| SCHEMBL13704120 | 0.78 | GPR3 (0.60) | MEN1KMT2AATMALDH1A1HSD17B10 | |
| SCHEMBL13704044 | 0.78 | GPR3 (0.60) | MEN1KMT2AATMALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183236-B1 | METHOD FOR THE PRODUCTION OF 18F-LABELED ACTIVE ESTERS AND THEIR APPLICATION EXEMPLIFIED BY THE PREPARATION OF A PSMA-SPECIFIC PET-TRACER | MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WSS (DE) | 2022-04-20 | — | — | EP | disclosed |
| EP-2388003-B1 | Colchicine derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |
| US-20210316006-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | MEDIMMUNE LIMITED (GB) | 2021-10-14 | — | — | US | disclosed |
| WO-2021106627-A1 | POLYIMIDE, POLYIMIDE RESIN FILM, MULTILAYER BODY AND FLEXIBLE DEVICE | 東レ株式会社 | 2021-06-03 | — | — | WO | disclosed |
| EP-3207929-B1 | COLCHICINE DERIVATIVES FOR THE TREATMENT OF CANCER | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10894239-B2 | Dispersant, dispersion composition, and fibrous sheet | MEISEI CHEMICAL WORKS, LTD. (JP) | 2021-01-19 | — | — | US | disclosed |
| EP-3279236-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| EP-3377510-B1 | GALNAC CLUSTER PHOSPHORAMIDITE | HOFFMANN LA ROCHE (CH) | 2020-12-02 | — | — | EP | disclosed |
| US-20200362177-A1 | FLUOROPOLYMER COMPOSITION | SOLVAY SPECIALTY POLYMERS IT (US) | 2020-11-19 | — | — | US | disclosed |
| US-20200309782-A1 | INTRACELLULAR DELIVERY VEHICLE | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2020-10-01 | — | — | US | disclosed |
| EP-1528923-A1 | N-((3-OXO-2,3-DIHYDRO-1H-ISOINDOL-1-YL)ACETYL)GUANIDINE DERIVATIVES AS NHE1-INHIBITORS FOR THE TREATMENT OF INFARCTION AND ANGINA PECTORIS | Aventis Pharma Deutschland GmbH (DE) | 2005-05-11 | — | — | EP | disclosed |
| US-20050051438-A1 | Electrosynthesis of organic compounds | QUEEN'S UNIVERSITY OF BELFAST, THE (GB) | 2005-03-10 | — | — | US | disclosed |
| EP-1404896-A2 | ELECTROSYNTHESIS OF ORGANIC COMPOUNDS | The Queen's University of Belfast (GB) | 2004-04-07 | — | — | EP | disclosed |
| US-20040048916-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | AVENTIS PHARMA DEUSCHLAND GMBH (DE) | 2004-03-11 | — | — | US | disclosed |
| WO-2003101450-A1 | N- ((3-OXO2, 3-DIHYDRO-1H-ISOINDOL-1-YL) ACETYL) GUANIDINE DERIVATIVES AS NHE-1 INHIBITORS FOR THE TREATMENT OF INFARCTION AND ANGINA PECTORIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | WO | disclosed |
| WO-2003004727-A2 | ELECTROSYNTHESIS OF ORGANIC COMPOUNDS | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2003-01-16 | — | — | WO | disclosed |
| EP-0734383-B1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| US-5965576-A | Cyclic amide derivatives for treating asthma | ZENECA LIMITED (GB) | 1999-10-12 | — | — | US | disclosed |
| US-5705505-A | Cyclic amide derivatives for treating asthma | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| US-5589489-A | Cyclic amide derivatives for treating asthma | ZENECA LIMITED (GB) | 1996-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200309782-A1 | INTRACELLULAR DELIVERY VEHICLE | CHERP, ACTB, GOLT1B | MEN1 2207/4885KMT2A 4632/4885ATM 3692/4885 |
| US-20210316006-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | BCR, MCL1, CD79B | MEN1 2781/4885KMT2A 1395/4885ATM 4013/4885 |
| US-20040048916-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | TNNI3, NDUFB3, NDUFB11 | MEN1 3718/4885KMT2A 4806/4885ATM 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.