Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409650 | 0.83 | CHRM4 (0.54) | NAMPTGPR119TP53CHRM4 | |
| SCHEMBL25030059 | 0.81 | NAMPT (0.54) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL14990343 | 0.79 | NAMPT (0.56) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL9409411 | 0.77 | NAMPT (0.47) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL5577703 | 0.75 | NAMPT (0.57) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL14790769 | 0.74 | NAMPT (0.56) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL10243179 | 0.74 | NAMPT (0.58) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL2252152 | 0.74 | GPR119 (0.60) | NAMPTPDE4BGPR119TP53WNT3A | |
| SCHEMBL9409500 | 0.74 | HDAC4 (0.48) | NAMPTGPR119HDAC6 | |
| SCHEMBL25030057 | 0.73 | NAMPT (0.53) | NAMPTPDE4BGPR119TP53WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |