Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409411 | 0.84 | NAMPT (0.47) | TP53GPR119NAMPTLMNAKDM4E | |
| SCHEMBL25030059 | 0.84 | NAMPT (0.54) | TP53GPR119NAMPTKDM4EPKM | |
| SCHEMBL25248877 | 0.83 | ACHE (0.63) | CHRM4 | |
| SCHEMBL9409443 | 0.83 | NAMPT (0.46) | CHRM4TP53GPR119NAMPT | |
| SCHEMBL14990343 | 0.82 | NAMPT (0.56) | TP53GPR119NAMPTKDM4EPKM | |
| Hydrochloric Acid SCHEMBL9409567 | 0.81 | CHRM4 (0.48) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL594491 | 0.81 | KDM4E (0.51) | GPR119KDM4EPKM | |
| SCHEMBL3020170 | 0.81 | RECQL (0.51) | CHRM4TP53GPR119NAMPTLMNA | |
| SCHEMBL9409500 | 0.80 | HDAC4 (0.48) | GPR119NAMPTLMNAKDM4EPKM | |
| SCHEMBL27413698 | 0.80 | NAMPT (0.46) | GPR119NAMPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |