Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386235 | 0.86 | CRBN (0.47) | MAPTKDM4EALDH1A1HTTHSD17B10 | |
| SCHEMBL15956007 | 0.77 | CA1 (0.53) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL27411611 | 0.75 | CYP2D6 (0.43) | MAPTKDM4EALDH1A1PIM1CA1 | |
| SCHEMBL13163353 | 0.75 | TDP1 (0.47) | MAPTKDM4EALDH1A1HTTHSD17B10 | |
| SCHEMBL25007019 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL12898108 | 0.74 | OPRM1 (0.51) | KDM4EALDH1A1HTTPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL9409391 | 0.73 | CYP2D6 (0.43) | MAPTKDM4EALDH1A1PIM1CA1 | |
| SCHEMBL14667564 | 0.73 | CA1 (0.48) | MAPTKDM4EALDH1A1HTTCA1 | |
| SCHEMBL31386351 | 0.72 | CA1 (0.41) | MAPTKDM4EALDH1A1HTTPIM1 | |
| SCHEMBL4434624 | 0.71 | CA1 (0.40) | MAPTKDM4EALDH1A1HTTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |