Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181896 | 0.92 | HDAC4 (0.57) | KMT2AHDAC4POLBNAMPTLCK | |
| SCHEMBL9409500 | 0.84 | HDAC4 (0.48) | KMT2AHDAC4POLBNAMPTLCK | |
| SCHEMBL14161696 | 0.81 | KMT2A (0.46) | KMT2AHDAC4POLBNAMPTLCK | |
| SCHEMBL20354579 | 0.81 | NAMPT (0.58) | KMT2ANAMPTKDM4EPKMALDH1A1 | |
| SCHEMBL3705072 | 0.80 | HDAC4 (0.54) | KMT2AHDAC4POLBNAMPTKDM4E | |
| SCHEMBL3697118 | 0.80 | HDAC4 (0.54) | KMT2AHDAC4POLBNAMPTKDM4E | |
| SCHEMBL17572994 | 0.80 | HDAC4 (0.60) | KMT2AHDAC4POLBKDM4EPKM | |
| SCHEMBL1199259 | 0.80 | NAMPT (0.57) | KMT2ANAMPTKDM4EPKMLMNA | |
| SCHEMBL1198897 | 0.80 | NAMPT (0.60) | KMT2ANAMPTKDM4EPKMALDH1A1 | |
| SCHEMBL28457523 | 0.79 | ALDH1A1 (0.70) | KMT2AHDAC4LMNAALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |