Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.48 |
| ▸ | ITGAV | P06756 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 4/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9409524 | 0.99 | ITGB3 (0.47) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL9409603 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9409373 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL9409661 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9409538 | 0.90 | ITGB3 (0.50) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9409607 | 0.87 | ITGB3 (0.47) | ITGB3ITGA2BITGAVTLR2ITGB1 | |
| Hydrochloric Acid SCHEMBL9409395 | 0.86 | CCR5 (0.48) | — | |
| Hydrochloric Acid SCHEMBL9409560 | 0.85 | TLR2 (0.50) | ITGB3ITGA2BTLR2 | |
| SCHEMBL9409475 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9409662 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | claimed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |