Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213350 | 0.82 | ESR2 (0.54) | DRD1HTR2AESR1ESR2DRD2 | |
| Methylamine SCHEMBL27550784 | 0.81 | DRD1 (0.50) | DRD1HTR2AESR1ESR2DRD2 | |
| SCHEMBL28033988 | 0.69 | ESR1 (0.54) | ESR1ESR2DRD2MAOAMAOB | |
| SCHEMBL8348394 | 0.69 | ESR1 (0.54) | ESR1ESR2DRD2MAOAMAOB | |
| SCHEMBL25804589 | 0.68 | SLC6A4 (0.46) | DRD1DRD2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL18408045 | 0.68 | ESR1 (0.50) | ESR1ESR2DRD2MAOAMAOB | |
| SCHEMBL18350076 | 0.68 | ESR1 (0.50) | ESR1ESR2DRD2MAOAMAOB | |
| Methylamine SCHEMBL27525680 | 0.68 | ESR1 (0.50) | ESR1ESR2DRD2CYP19A1 | |
| SCHEMBL1513372 | 0.68 | ESR1 (0.43) | DRD1ESR1ESR2DRD2MAOA | |
| SCHEMBL1513537 | 0.68 | ESR1 (0.43) | DRD1ESR1ESR2DRD2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581058-A1 | Polyaryl ether films | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | disclosed |