Methylamine

Methylamine

SCHEMBL27550784

CN.CN.CN.Oc1ccc(C2CCc3ccc(O)cc32)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 5/20 0.50
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
HTR2A P28223 1/20 0.50
DRD2 P14416 3/20 0.49
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
LMNA P02545 1/20 0.44
DRD3 P35462 1/20 0.44
OPRK1 P41145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11213350 0.95 ESR2 (0.54) DRD1ESR1ESR2HTR2ADRD2
Methylamine SCHEMBL27525680 0.87 ESR1 (0.50) ESR1ESR2DRD2CYP19A1DRD3
Methylamine SCHEMBL27580406 0.83 SIGMAR1 (0.48) DRD1
SCHEMBL9409776 0.81 DRD1 (0.45) DRD1ESR1ESR2HTR2ADRD2
SCHEMBL8938850 0.79 IGF1R (0.61) DRD1DRD2DRD3
Methylamine SCHEMBL27503460 0.78 DRD1 (0.51) DRD1HTR2ADRD2CYP19A1
SCHEMBL1871239 0.77 SIGMAR1 (0.47) DRD1DRD2
SCHEMBL24684598 0.74 DRD1 (0.50) DRD1DRD2CYP19A1CYP11B1
SCHEMBL25804589 0.74 SLC6A4 (0.46) DRD1DRD2CYP2D6SLC6A2SLC6A4
SCHEMBL1370804 0.73 DRD2 (0.55) ESR1ESR2DRD2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103497334-A Copolyetherimides SABIC INNOVATIVE PLASTICS IP 2014-01-08 CN claimed
CN-103249758-A Isosorbide-containing polycarbonates and their preparation SABIC INNOVATIVE PLASTICS IP 2013-08-14 CN claimed
CN-1938379-B Impact-modified compositions and methods GEN ELECTRIC 2012-05-16 CN claimed
CN-100554332-C The goods that polycarbonate molding compositions and specious degree thereof improve GEN ELECTRIC (NL) 2009-10-28 CN claimed
CN-100535029-C Method for producing copolyestercarbonates GEN ELECTRIC (NL) 2009-09-02 CN claimed
CN-101374908-A Foamed and foamable high glass transition temperature polymers GEN ELECTRIC (US) 2009-02-25 CN claimed
CN-101370872-A Food service articles of manufacture comprising high temperature polymers GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101370873-A Annular or tubular shaped articles of novel polymer blends GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101351506-A High glass transition temperature thermoplastic articles GEN ELECTRIC (US) 2009-01-21 CN claimed
CN-100451071-C Flame-retardant resin composition and method for producing the same GEN ELECTRIC (NL) 2009-01-14 CN claimed
CN-1938379-A Impact-modified compositions and methods GEN ELECTRIC (US) 2007-03-28 CN claimed
CN-1286877-C Method for copolyestercarbonate synthesis GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1871280-A Phase transfer catalytic process for the preparation of polyetherimides GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1871195-A Method for making salts hydroxy-substituted hydrocarbons GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1867605-A Method for preparing copolyestercarbonates GEN ELECTRIC (US) 2006-11-22 CN claimed
CN-1272382-C Flame retardant resinous compositions and method GEN ELECTRIC (US) 2006-08-30 CN claimed
CN-1688650-A Flame retardant resinous compositions and method GEN ELECTRIC (US) 2005-10-26 CN claimed
CN-1656141-A Method for copolyestercarbonate synthesis GEN ELECTRIC (US) 2005-08-17 CN claimed
CN-1612916-A Flame retardant resinous compositions and method GEN ELECTRIC (US) 2005-05-04 CN claimed
CN-1612917-A Flame retardant resinous compositions and method of making the same GEN ELECTRIC (US) 2005-05-04 CN claimed