3-Aminophenol

3-Aminophenol

SCHEMBL94098

Cc1ccc(N)cc1O.Nc1cccc(O)c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.73
TSHR P16473 2/20 0.73
ALDH1A1 P00352 3/20 0.65
CA12 O43570 2/20 0.65
CA2 P00918 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CA1 P00915 1/20 0.65
CA7 P43166 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
PDE10A Q9Y233 1/20 0.50
ACHE P22303 3/20 0.43
SIGMAR1 Q99720 1/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPC1 O15118 1/20 0.42
MITF O75030 1/20 0.42
POLB P06746 1/20 0.42
HSD17B1 P14061 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resorcinol SCHEMBL8059792 0.94 TSHR (0.76) CASP1TSHRALDH1A1CA12CA2
Phenol SCHEMBL27557181 0.86 CASP1 (0.76) CASP1TSHRALDH1A1CA12CA2
SCHEMBL4869221 0.85 CASP1 (1.00) CASP1TSHRALDH1A1CA2CA1
SCHEMBL93860 0.85
SCHEMBL29670126 0.85
3-Aminophenol SCHEMBL9861911 0.85 ALDH1A1 (0.65) CASP1TSHRALDH1A1CA12CA2
SCHEMBL7999222 0.82 CASP1 (0.76) CASP1TSHRALDH1A1CA12CA2
1-Naphthol SCHEMBL8002816 0.82 TSHR (0.49) CASP1TSHRALDH1A1CA12CA2
3-Aminophenol SCHEMBL679715 0.81 ALDH1A1 (1.00) CASP1TSHRALDH1A1CA12CA2
3-Aminophenol SCHEMBL29358017 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210060-B1 DEVELOPER-COUPLER COMBINATIONS HENKEL KGAA (DE) 2004-09-15 EP claimed
CN-103458863-B Comprise 1-hexyl/heptyl-4, the oxidative coloration composition of 5-diamino-pyrazole and benzo [1,3] dioxole-5-base amine and derivative thereof THE PROCTER & GAMBLE CO. (US) 2016-05-04 CN disclosed
EP-2425809-A1 Aqueous colouring composition KPSS-Kao Professional Salon Services GmbH (DE) 2012-03-07 EP disclosed