Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylphenylsulfide SCHEMBL21802110 | 0.91 | DPP4 (0.38) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL22558244 | 0.89 | DPP4 (0.37) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL2529222 | 0.89 | CES1 (0.45) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL19639862 | 0.83 | DPP4 (0.39) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL20533389 | 0.83 | ACHE (0.44) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL1673145 | 0.83 | KIF11 (0.38) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL20511991 | 0.82 | ACHE (0.42) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL21903711 | 0.81 | DPP4 (0.38) | DPP4DPP8DPP9DPP7KIF11 | |
| Methylphenylsulfide SCHEMBL10524350 | 0.79 | KIF11 (0.38) | DPP4DPP8DPP9DPP7KIF11 | |
| Trifluoroacetic Acid SCHEMBL5571447 | 0.78 | CA12 (0.44) | DPP4DPP7CES1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |