Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17398530 | 0.92 | KIF11 (0.47) | KIF11 | |
| SCHEMBL13050382 | 0.85 | KIF11 (0.45) | KIF11 | |
| SCHEMBL13523659 | 0.78 | KIF11 (0.51) | KIF11 | |
| SCHEMBL18704758 | 0.77 | SLC6A1 (0.44) | KIF11 | |
| SCHEMBL17447160 | 0.76 | KIF11 (0.58) | KIF11 | |
| SCHEMBL34785 | 0.76 | KIF11 (0.57) | KIF11 | |
| SCHEMBL22328130 | 0.73 | KIF11 (0.67) | KIF11 | |
| SCHEMBL12417494 | 0.73 | KIF11 (0.67) | KIF11 | |
| SCHEMBL13865453 | 0.73 | CYP2C19 (0.42) | KIF11 | |
| SCHEMBL11267943 | 0.73 | KIF11 (0.48) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618221-A2 | Heterocyclic inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-10-05 | — | — | EP | disclosed |