Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137891 | 0.84 | ALDH1A1 (0.49) | ALDH1A1PPARGPPARAPPARDGLA | |
| SCHEMBL9859946 | 0.82 | ALDH1A1 (0.63) | ALDH1A1PPARGPPARAPPARDMAPT | |
| SCHEMBL10529423 | 0.81 | ALDH1A1 (0.47) | ALDH1A1PPARGPPARAPPARDGLA | |
| SCHEMBL3148512 | 0.78 | ALDH1A1 (0.53) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL1354705 | 0.78 | ALDH1A1 (0.56) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL9091679 | 0.78 | ALDH1A1 (0.51) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL1356636 | 0.77 | ALDH1A1 (0.51) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL12558176 | 0.77 | TSHR (0.59) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL10697310 | 0.77 | TSHR (0.43) | ALDH1A1PPARGGLAMAPTMEN1 | |
| SCHEMBL8432636 | 0.76 | ALDH1A1 (0.50) | ALDH1A1PPARGGLAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611748-A1 | Propanolamine derivatives and their use as hypotensive or antiglaucoma agents | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-24 | — | — | EP | claimed |