Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410270 | 0.90 | KMT2A (0.52) | KMT2ALMNAMEN1TSHRALDH1A1 | |
| SCHEMBL9359743 | 0.87 | TSHR (0.53) | KMT2ALMNASMN1; SMN2TSHRGAA | |
| SCHEMBL9410284 | 0.87 | ALDH1A1 (0.48) | KMT2AMEN1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9410318 | 0.86 | TSHR (0.51) | KMT2ALMNAMEN1SMN1; SMN2TSHR | |
| SCHEMBL11175662 | 0.85 | TSHR (0.55) | KMT2AMEN1TSHRGAACYP2D6 | |
| SCHEMBL9410338 | 0.85 | TSHR (0.55) | KMT2AMEN1TSHRGAACYP2D6 | |
| SCHEMBL9410296 | 0.84 | KMT2A (0.46) | KMT2ALMNAMEN1SMN1; SMN2TSHR | |
| SCHEMBL9410280 | 0.82 | TSHR (0.57) | KMT2AMEN1TSHRGAA | |
| SCHEMBL11186095 | 0.82 | KMT2A (0.52) | KMT2ALMNAMEN1SMN1; SMN2TSHR | |
| SCHEMBL9410286 | 0.81 | KMT2A (0.54) | KMT2ALMNAMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |