Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410314 | 0.96 | TSHR (0.38) | TSHRMAOBMAOAACHEGAA | |
| SCHEMBL9410297 | 0.84 | TSHR (0.45) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL6453784 | 0.81 | GAA (0.48) | TSHRMAOBMAOAACHEGAA | |
| SCHEMBL11296773 | 0.80 | KMT2A (0.41) | TSHRMAOBMAOAACHEGAA | |
| SCHEMBL9410279 | 0.80 | TSHR (0.47) | TSHRGAAALDH1A1KMT2AADRB2 | |
| SCHEMBL9413672 | 0.79 | MAOB (0.41) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL11176796 | 0.79 | KMT2A (0.39) | GAAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9410284 | 0.79 | ALDH1A1 (0.48) | TSHRGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2958675 | 0.77 | ALOX5 (0.44) | MAOBMAOAACHEGAAALDH1A1 | |
| SCHEMBL11175662 | 0.77 | TSHR (0.55) | TSHRGAAKMT2AMEN1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |