Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410335 | 0.91 | TSHR (0.51) | TSHRKMT2AGAAMEN1THRB | |
| SCHEMBL9410390 | 0.88 | TSHR (0.55) | TSHRKMT2AGAAMEN1THRB | |
| SCHEMBL9410320 | 0.88 | TSHR (0.48) | TSHRKMT2AGAAMEN1ABCB1 | |
| SCHEMBL9410281 | 0.86 | KMT2A (0.57) | TSHRKMT2AGAAMEN1ABCB1 | |
| SCHEMBL9410319 | 0.86 | TSHR (0.57) | TSHRKMT2AGAAMEN1ABCB1 | |
| SCHEMBL9410354 | 0.86 | TSHR (0.57) | TSHRKMT2AGAAMEN1HTR3E | |
| SCHEMBL11180464 | 0.86 | TSHR (0.57) | TSHRKMT2AGAAMEN1HTR3E | |
| SCHEMBL11184014 | 0.83 | TSHR (0.54) | TSHRKMT2AGAAMEN1HTR3E | |
| SCHEMBL9410264 | 0.83 | TSHR (0.48) | TSHRKMT2AGAAMEN1THRB | |
| SCHEMBL9410336 | 0.83 | TSHR (0.48) | TSHRKMT2AGAAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |