Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410468 | 0.85 | LMNA (0.55) | PPARGPPARDPPARAL3MBTL1SCN3A | |
| SCHEMBL9319345 | 0.81 | LMNA (0.42) | L3MBTL1SCN3AROCK2GALR3RAB9A | |
| SCHEMBL9410490 | 0.78 | SCN3A (0.36) | PPARGPPARDPPARASCN3AROCK2 | |
| SCHEMBL9410414 | 0.77 | LMNA (0.54) | PPARGPPARDPPARAL3MBTL1GALR3 | |
| SCHEMBL9410427 | 0.75 | LMNA (0.41) | L3MBTL1SCN3AROCK2GALR3RAB9A | |
| SCHEMBL9410381 | 0.74 | SMN1; SMN2 (0.41) | PPARGPPARDPPARAL3MBTL1SCN3A | |
| SCHEMBL9410452 | 0.74 | SMN1; SMN2 (0.39) | L3MBTL1SCN3AROCK2GALR3RAB9A | |
| SCHEMBL9410471 | 0.72 | LMNA (0.53) | L3MBTL1MAPTGALR3RAB9ANR3C1 | |
| SCHEMBL25471877 | 0.72 | SMN1; SMN2 (0.49) | L3MBTL1MAPTRAB9AALDH1A1 | |
| SCHEMBL9410392 | 0.71 | SMN1; SMN2 (0.62) | PPARGPPARDPPARAL3MBTL1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366991-A | Agriculture | ENI CHEM SYNTHESIS S.P.A. (IT) | 1994-11-22 | — | — | US | disclosed |
| EP-0590720-A1 | Pyrazolecarboxamides exhibiting insecticidal and acaricidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-04-06 | — | — | EP | disclosed |