Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410427 | 0.95 | LMNA (0.41) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9319345 | 0.92 | LMNA (0.42) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410405 | 0.88 | LMNA (0.44) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410381 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410403 | 0.82 | RAB9A (0.39) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410468 | 0.81 | LMNA (0.55) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410445 | 0.80 | LMNA (0.47) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410493 | 0.75 | EPHX2 (0.40) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410414 | 0.74 | LMNA (0.54) | SMN1; SMN2LMNARAB9AGALR3NR2F2 | |
| SCHEMBL9410383 | 0.74 | PPARG (0.45) | RAB9AGALR3L3MBTL1SCN3ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366991-A | Agriculture | ENI CHEM SYNTHESIS S.P.A. (IT) | 1994-11-22 | — | — | US | disclosed |
| EP-0590720-A1 | Pyrazolecarboxamides exhibiting insecticidal and acaricidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-04-06 | — | — | EP | disclosed |