Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940961 | 0.90 | SLC5A2 (0.54) | NPC1RAB9ASLC5A2APPPTPN1 | |
| SCHEMBL941509 | 0.90 | MAOB (0.58) | NPC1RAB9APPARGPPARDPPARA | |
| SCHEMBL941331 | 0.88 | PPARG (0.55) | NPC1RAB9APPARGPPARDPPARA | |
| SCHEMBL4635640 | 0.84 | NPC1 (0.68) | NPC1RAB9AAKR1B1DPP4PTPN1 | |
| SCHEMBL14975517 | 0.81 | SLC5A2 (0.61) | SLC5A2PPARGPPARDPPARASLC5A1 | |
| SCHEMBL16227542 | 0.81 | SLC5A2 (0.61) | SLC5A2PPARGPPARDPPARASLC5A1 | |
| SCHEMBL14975518 | 0.81 | SLC5A2 (0.61) | SLC5A2PPARGPPARDPPARASLC5A1 | |
| SCHEMBL8652659 | 0.80 | APP (0.55) | SLC5A2APPPTPN1PPARGPPARD | |
| SCHEMBL28867299 | 0.80 | TYR (0.66) | SLC5A2PPARGPPARDPPARASLC5A1 | |
| SCHEMBL943278 | 0.80 | MAOB (0.58) | PPARGPPARDPPARASLC5A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110014141-A1 | TOPICAL AGENT FOR DERMATOLOGICAL USE | DSM IP ASSETS B.V. (NL) | 2011-01-20 | — | — | US | disclosed |
| EP-1859835-A2 | Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside | PENTAPHARM Ltd. (CH) | 2007-11-28 | — | — | EP | disclosed |
| US-20030198610-A1 | Topical agent for dermatological use | DSM IP ASSETS B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014141-A1 | TOPICAL AGENT FOR DERMATOLOGICAL USE | GALE, ALPP, UGGT1 | NPC1 2633/4885RAB9A 4832/4885SLC5A2 1353/4885 |
| US-20030198610-A1 | Topical agent for dermatological use | GALE, UGGT1, UGDH | NPC1 2969/4885RAB9A 4806/4885SLC5A2 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.